News

  • Recent Publication: Mobility Separation and UVPD of Co-Adducted Tetrasaccharides Ultraviolet photodissociation (UVPD) has had its application directed primarily at biomolecule analysis, but with a common drawback of low fragment abundances. We encountered this same problem with UVPD of two sodiated isomeric glycans, but found a significantly higher fragment yield from the cobalt adducts of those same tetrasaccharides. An additional bonus was that the cobalt ...
  • Animation: Improving Rp by Increasing DT Cell Length Austen has recently assembled an animation demonstrating the effect of increasing drift tube length on resolving power, calculated from peak width contributions from diffusion and gate pulse width. Click the image to view.
  • Recent Publication: Enhanced Mixture Separations of Metal Adducted Tetrasaccharides Using a combination of Fourier transform ion mobility and ion trap mass spectrometry Kelsey demonstrated the degree to which different metal cations were able to enhance isomer separations across a set of tetrasaccharides.  While full resolution was not achieved for the full set of 5 isomers this work demonstrates the current state of the art for ...
  • Open-Source, Modular Approaches to Ion Mobility Spectrometry Outside of an ionization source and a Faraday plate, a drift tube IMS system is fundamentally comprised of 5 primary components: Reaction/Drift Cell Ion Gate Gate Pulsing Electronics Current to Voltage Converter Data Acquisition System (DAQ) Within the IMS research community hardware and DAQ solutions are often custom and rarely replicated exactly. In an effort to address this knowledge and resource gap, ...
  • Fourier Transform Ion Mobility-Ion Trap Mass Spectrometry We are pleased to report the publication of our work outlining the effective coupling of a drift tube IMS system with an ion trap mass spectrometer.  Compared to previous implementations (see our 2005 publication) we have dramatically improved the IMS duty cycle by encoding the mobility information in the frequency domain.  Using this Fourier approach ...
  • Dr. Clowers Recognized for Early Career Achievement In the Spring Semester of 2015, Dr. Clowers was recognized within the College of Arts and Sciences at Washington State University for Early Career Achievement.  The College of Arts and Sciences celebrated achievements in teaching, research, and mentoring at its third annual Appreciation and Recognition Social on April 22, 2015.  Dr. Clowers was one of ...
  • IMS Short Course Worksheet For those that are interested, here is the spreadsheet used in the ASMS 2016 short course.  Thank Dr. Bill Siems if you see him.   Ion Mobility Cal v3
  • Live from Fulmer Hall: Waters G2 We are pleased to announce the unpacking and, more importantly, the successful pump down of the G2.  Combined with a new UPLC unit we anticipate this instrument playing a large role in future metabolomics work in our laboratory. Kudos to Justin Chang from Waters for executing the pump down sequence like a champ.   ...
  • Waters G2 at WSU Unboxing to commence in t-minus 6 days and counting…
  • IMS – Ion Trap Equipped with UV Photofragmentation   In early 2015 the research group is pleased to bring the next generation ion mobility-ion trap system online.  This system is equipped with two ion gates which allows the speed of the IMS to be effectively coupled to the slow scan speeds of traditional ion trapping experiments.  Though not as fast as tradition IMS-TOF configurations, ...

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